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Additional limitations were minimal BD data

At 28C with light protection, the complex remained 95%+ intact for 28 days

ABSTRACT UDP-glucuronosyltransferase (UGT) enzymes comprise a superfamily of key proteins that catalyze the glucuronidation reaction on a wide range of structurally diverse endogenous and exogenous chemicals

Absorption, distribution, metabolism, and excretion of [(14)C]-Sotorasib in rats and dogs: interspecies differences in absorption, protein conjugation and metabolism